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To learn more about Triangle CERSI, join our mailing list for future communications.

To learn more about Triangle CERSI, join our mailing list for future communications.

To learn more about Triangle CERSI, join our mailing list for future communications.

To learn more about Triangle CERSI, join our mailing list for future communications.

To learn more about Triangle CERSI, join our mailing list for future communications.

To learn more about Triangle CERSI, join our mailing list for future communications.

Triangle 003: Enhancing the role of pharmacies in reducing opioid misuse and abuse

Research

Enhancing the role of pharmacies in reducing opioid misuse and abuse

CERSI P.I.s and Collaborators
Tamera Hughes, Pharm.D, Ph.D (High Point University); Stefanie Ferreri, Pharm.D. (UNC-CH); Delesha Carpenter, Ph.D., M.S.P.H. (UNC-Asheville); Lori Armistead, Pharm.D. (UNC-CH); Tamara Baker, PhD (UNC-CH); Abby Gamble (UNC-Asheville)

FDA SMEs and Collaborators
Olga Rass, PhD; Caroline Huang, PhD; Veronica Uzoebo, EdD, MBA, MS, MA; Blair Coleman, PhD, MPH; Lukas Glos, MA; Henry Appiah, PharmD; Sheheryar Muhammad, PharmD; Amy Seitz, PhD, MPH; Candice Collins, DrPH; Mitra Ahadpour, MD, DABAM; Nancy Chang, MD; Sandrine Ly, PharmD; Paula Rausch, PhD, RN; Brian Gac, PharmD; Hillary Dolinsky, MBA, MSW; Christine Lee, PharmD, PhD; Julie Hsieh, PhD, MPH

The misuse of opioid medications harms many people, impacting both patients and communities. Some populations and geographic areas have sparse support services for opioid misuse, resulting in greater health harms. 

The rate of opioid overdose deaths has recently increased in the United States for those living in rural areas.

We need to find new ways to help reduce harms from opioid misuse by supporting treatment for opioid use disorder and increasing access to medications that reverse opioid overdoses for all people, regardless of where they live or who they are. Community pharmacies, also called retail pharmacies, can help.

Project Description and Goals

The goal of this project is to understand how community pharmacies work collaboratively with patients to reduce the harm that opioid misuse can cause. We are also seeking to understand what challenges community pharmacies face when trying to decrease harm from opioids by supporting safe use of opioid medications and access to medications for opioid use disorder treatment and opioid overdose reversal.

We are focusing our information gathering efforts on community pharmacies in rural areas and communities representative of the US population, since these are the areas of highest need according to recent trends in opioid overdose deaths. We are sending out surveys and interviewing pharmacists, pharmacy technicians, patients, and other community members to achieve these goals. Ultimately, we want to explore effective ways to reduce the harm from opioid misuse among communities currently in need.

Publications
  1. Ferreri, S.P., Ngo, P.Q., Yen, K.D. et al. Examining rural community pharmacists’ knowledge and practices in opioid overdose prevention and treatment services in the Southeastern United States. Harm Reduct J 23, 11 (2026). https://doi.org/10.1186/s12954-025-01364-z
How does this project fit into the FDA's Regulatory Science Framework?

This project aims to invigorate public health preparedness and response of the FDA toward addressing substance use and misuse in patients & consumers.

PI in the news: Dr. Delesha Carpenter

Learn how Triangle CERSI's Dr. Delesha Carpenter is making an impact through regulatory science.